Methylvax

Compsition:

Each 1 gm contains: 

Phenoxymethylpenicillin  potassium 887 mg

 ( eq. to phenoxymethylpenicillin base  800 mg )

Properties:

•  Phenoxymethylpenicillin  is a narrow-spectrum penicillin with activity mainly against gram-positive bacteria (e.g: Bacillus anthracis, Clostridium spp (not C. difficile), Fusobacterium, and Actinomyces)  
• Phenoxymethylpenicillin as all other penicillins, exerts a bactericidal action on bacteria during the stage of active multiplication. It forms an irreversible binding to penicillin-binding-proteins (PBPs), enzymes that facilitate the formation of cross-links of peptidoglycan chains in the synthesis of the bacterial cell wall. This results in abnormal cell growth and cytolysis of the cell.

Target Species : 

Broiler chickens

Indications :  

Treatment of necrotic enteritis caused by Clostridium perfringens.  

Dosage and adminsration: 

Dosage form : powder for oral solution 

Route: Orally with drinking water.

• For Whole product :

0.17— 0.25 gm  of product / liter drinking water daily for 5 days
Warnings and percuations:

                Plentiful water supply.

• The administration of the product may lead to an increase in medicated water consumption.
• Use of the product should be based on susceptibility testing of the bacteria isolated from chickens that have already died on the farm.
• The product should not be used to compensate for poor hygiene and management of the chicken houses.
• Do not combine with bacteriostatic antibiotics.

Contra-indications :

• Do not use in case of hypersensitivity to the active substance.

Side effects:

• Although no adverse reactions have been seen after the administration of the product, penicillins may cause diarrhoea and alter gut flora with selecting resistant bacteria.

Withdrwal time:

Meat and offal:  2 days.

Eggs:  zero days.

Storage condations:

  Store at a temperature not exceeding  30°C in a dry place, used immediately after opening and reconstitution.

Packaging :

250 gm of product in transparent colorless plastic HDPE bag in opaque plastic HDPE container closed by opaque plastic HDPE cap with an outer label only.